Periodontal disease and incident venous thromboembolism: The Atherosclerosis Risk in Communities study.

ABSTRACT:

Aim

Periodontal disease is a cardiovascular disease (CVD) risk factor but few studies have considered the relationship between periodontal disease and venous thromboembolism (VTE). We hypothesized that periodontal disease is independently associated with increased risk of incident VTE.

Materials and methods

We used data from 8,092 participants of the Atherosclerosis Risk in Communities (ARIC) study to examine periodontal disease in 1996-1998 and incident VTE through 2011. Periodontal disease was determined using self-reported tooth loss due to gum disease and dental examinations. Cox proportional hazards regression models were used to estimate hazard ratios for VTE and 95% confidence intervals adjusted for relevant confounders.

Results and conclusions

Participants wer

SUBMITTER: Cowan LT 

PROVIDER: S-EPMC6340749 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature