Ontology highlight
ABSTRACT:
SUBMITTER: Kouno T
PROVIDER: S-EPMC6341120 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Nature communications 20190121 1
Single-cell transcriptomic profiling is a powerful tool to explore cellular heterogeneity. However, most of these methods focus on the 3'-end of polyadenylated transcripts and provide only a partial view of the transcriptome. We introduce C1 CAGE, a method for the detection of transcript 5'-ends with an original sample multiplexing strategy in the C1<sup>TM</sup> microfluidic system. We first quantifiy the performance of C1 CAGE and find it as accurate and sensitive as other methods in the C1 sy ...[more]