Population structure of human gut bacteria in a diverse cohort from rural Tanzania and Botswana.

ABSTRACT:

Background

Gut microbiota from individuals in rural, non-industrialized societies differ from those in individuals from industrialized societies. Here, we use 16S rRNA sequencing to survey the gut bacteria of seven non-industrialized populations from Tanzania and Botswana. These include populations practicing traditional hunter-gatherer, pastoralist, and agropastoralist subsistence lifestyles and a comparative urban cohort from the greater Philadelphia region.

Results

We find that bacterial diversity per individual and within-population phylogenetic dissimilarity differs between Botswanan and Tanzanian populations, with Tanzania generally having higher diversity per individual and lower dissimilarity between individuals. Among subsistence groups, the gut bacteria of hunter-g

SUBMITTER: Hansen MEB 

PROVIDER: S-EPMC6341659 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature