Low-dose aspirin and burr-hole drainage of chronic subdural hematoma: study protocol for a randomized controlled study.

ABSTRACT:

Background

Low-dose acetylsalicylic acid (ASA) in patients with chronic subdural hematoma (cSDH) represents a significant neurosurgical challenge. While continuation of ASA during the perioperative phase might increase recurrence and bleeding rates, discontinuation increases the risk of thromboembolic events. The aim of this study is to compare the postoperative recurrence and cardiovascular complication rates of patients undergoing burr-hole trepanation for cSDH with and without discontinuation of ASA.

Methods

In this prospective randomized, placebo-controlled, double-blinded study we include all patients undergoing burr-hole drainage of cSDH who are under ASA treatment. The patients are randomized into two groups, one receiving ASA and the other placebo perioperatively. Th

SUBMITTER: Kamenova M 

PROVIDER: S-EPMC6341728 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature