Use of genome-scale models to get new insights into the marine actinomycete genus Salinispora.

ABSTRACT:

Background

There is little published regarding metabolism of Salinispora species. In continuation with efforts performed towards this goal, this study is focused on new insights into the metabolism of the three-identified species of Salinispora using constraints-based modeling. At present, only one manually curated genome-scale metabolic model (GSM) for Salinispora tropica strain CNB-440^T has been built despite the role of Salinispora strains in drug discovery.

Results

Here, we updated, and expanded the scope of the model of Salinispora tropica CNB-440^T, and GSMs were constructed for two sequenced type strains covering the three-identified species. We also constructed a Salinispora core model that contains the genes shared by 93 sequenced strains and a

SUBMITTER: Contador CA 

PROVIDER: S-EPMC6341766 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature