Plug-N-Play: Mechanotransduction Goes Modular.

ABSTRACT: Mechanosensitive ion channels initiate sensory signals by converting mechanical information into electrochemical signals. In this issue of Neuron (Zhao et al., 2016), a data-rich structure-function study on mammalian mechanosensitive Piezo channels reveals a modular protein architecture that includes a central pore module surrounded by a force-sensing module.

SUBMITTER: Akyuz N 

PROVIDER: S-EPMC6341990 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature