Measuring transient phase-amplitude coupling using local mutual information.

ABSTRACT: Here we demonstrate the suitability of a local mutual information measure for estimating the temporal dynamics of cross-frequency coupling (CFC) in brain electrophysiological signals. In CFC, concurrent activity streams in different frequency ranges interact and transiently couple. A particular form of CFC, phase-amplitude coupling (PAC), has raised interest given the growing amount of evidence of its possible role in healthy and pathological brain information processing. Although several methods have been proposed for PAC estimation, only a few have addressed the estimation of the temporal evolution of PAC, and these typically require a large number of experimental trials to return a reliable estimate. Here we explore the use of mutual information to estimate a PAC measure (MIPAC) in both

SUBMITTER: Martinez-Cancino R 

PROVIDER: S-EPMC6342492 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature