Long-term risk of screen-detected and interval breast cancer after false-positive results at mammography screening: joint analysis of three national cohorts.

ABSTRACT: BACKGROUND:We assessed the long-term risk of screen-detected and interval breast cancer in women with a first or second false-positive screening result. METHODS:Joint analysis had been performed using individual-level data from three population-based screening programs in Europe (Copenhagen in Denmark, Norway, and Spain). Overall, 75,513 screened women aged 50-69 years from Denmark (1991-2010), 556,640 from Norway (1996-2008), and 517,314 from Spain (1994-2010) were included. We used partly conditional Cox hazards models to assess the association between false-positive results and the risk of subsequent screen-detected and interval cancer. RESULTS:During follow-up, 1,149,467 women underwent 3,510,450 screening exams, and 10,623 screen-detected and 5700 interval cancers were diagnosed. Comp

SUBMITTER: Roman M 

PROVIDER: S-EPMC6342908 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature