Associations between childhood maltreatment and inflammatory markers.

ABSTRACT:

Background

Childhood maltreatment is one of the strongest predictors of adulthood depression and alterations to circulating levels of inflammatory markers is one putative mechanism mediating risk or resilience.AimsTo determine the effects of childhood maltreatment on circulating levels of 41 inflammatory markers in healthy individuals and those with a major depressive disorder (MDD) diagnosis.

Method

We investigated the association of childhood maltreatment with levels of 41 inflammatory markers in two groups, 164 patients with MDD and 301 controls, using multiplex electrochemiluminescence methods applied to blood serum.

Results

Childhood maltreatment was not associated with altered inflammatory markers in either group after multiple testing correction. Body mass inde

SUBMITTER: Palmos AB 

PROVIDER: S-EPMC6343120 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature