Aspirin reduces long-term stroke risk in women with prior hypertensive disorders of pregnancy.

ABSTRACT:

Objective

To determine whether hypertensive disorders of pregnancy (HDP) increased long-term stroke risk in women in the California Teachers Study (CTS), a prospective cohort study, and whether aspirin or statin use modified this risk.

Methods

CTS participants ≤60 years of age at the time of enrollment in 1995 were followed up prospectively for validated stroke outcomes obtained via linkage with California hospital records through December 31, 2015. We calculated unadjusted and adjusted hazard ratios (HRs) and 95% confidence intervals (95% CIs) for the primary outcomes of all stroke and stroke before 60 years of age among those with and without a history of HDP. We tested for interactions (p < 0.2) and performed stratified analyses to assess the risk of the primary ou

SUBMITTER: Miller EC 

PROVIDER: S-EPMC6345119 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature