Preliminary investigation of brown adipose tissue assessed by PET/CT and cancer activity.

ABSTRACT:

Objective

To determine the role of brown adipose tissue (BAT) in cancer activity.

Materials and methods

The study group comprised 142 patients (121 female, 21 male; mean age, 49 ± 16 years) who underwent F18-FDG PET/CT (PET/CT) for staging or surveillance of cancer and who were BAT-positive on PET/CT. BAT volume by PET/CT, abdominal (visceral and subcutaneous) fat and paraspinous muscle cross-sectional areas (CSA) were assessed. Groups with and without active cancer on PET/CT were compared using a two-sided paired t test. Linear regression analyses between BAT and body composition parameters were performed.

Results

There were 62 patients (54 female, eight male) who had active cancer on PET/CT and 80 patients (67 female, 13 male) without active cancer. Groups were simi

SUBMITTER: Bos SA 

PROVIDER: S-EPMC6345160 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature