Reward Processing in Depression: A Conceptual and Meta-Analytic Review Across fMRI and EEG Studies.

ABSTRACT:

Objective

A role for aberrant reward processing in the pathogenesis of depression has long been proposed. However, no review has yet examined its role in depression by integrating conceptual and quantitative findings across functional MRI (fMRI) and EEG methodologies. The authors quantified these effects, with an emphasis on development.

Method

A total of 38 fMRI and 12 EEG studies were entered into fMRI and EEG meta-analyses. fMRI studies primarily examined reward anticipation and reward feedback. These were analyzed using the activation likelihood estimation method. EEG studies involved mainly the feedback-related negativity (FRN) event-related potential, and these studies were analyzed using random-effects meta-analysis of the association between FRN and depression.

Re

SUBMITTER: Keren H 

PROVIDER: S-EPMC6345602 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature