Effort and Fatigue-Related Functional Connectivity in Mild Traumatic Brain Injury.

ABSTRACT: Mental fatigue in healthy individuals is typically observed under conditions of high cognitive demand, particularly when effort is required to perform a task for a long period of time-thus the concepts of fatigue and effort are closely related. In brain injured individuals, mental fatigue can be a persistent and debilitating symptom. Presence of fatigue after brain injury is prognostic for return to work/school and engagement in activities of daily life. As such, it should be a high priority for treatment in this population, but because there is little understanding of its behavioral and neural underpinnings, the target for such treatment is unknown. Here, the neural underpinnings of fatigue and effort are investigated in active duty military service members with mild traumatic brain injur

SUBMITTER: Ramage AE 

PROVIDER: S-EPMC6345685 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature