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The Y chromosome sequence of the channel catfish suggests novel sex determination mechanisms in teleost fish.


ABSTRACT:

Background

Sex determination mechanisms in teleost fish broadly differ from mammals and birds, with sex chromosomes that are far less differentiated and recombination often occurring along the length of the X and Y chromosomes, posing major challenges for the identification of specific sex determination genes. Here, we take an innovative approach of comparative genome analysis of the genomic sequences of the X chromosome and newly sequenced Y chromosome in the channel catfish.

Results

Using a YY channel catfish as the sequencing template, we generated, assembled, and annotated the Y genome sequence of channel catfish. The genome sequence assembly had a contig N50 size of 2.7 Mb and a scaffold N50 size of 26.7 Mb. Genetic linkage and GWAS analyses placed the sex determination

SUBMITTER: Bao L 

PROVIDER: S-EPMC6346536 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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