Multiple QTL underlie milk phenotypes at the CSF2RB locus.

ABSTRACT:

Background

Over many years, artificial selection has substantially improved milk production by cows. However, the genes that underlie milk production quantitative trait loci (QTL) remain relatively poorly characterised. Here, we investigate a previously reported QTL located at the CSF2RB locus on chromosome 5, for several milk production phenotypes, to better understand its underlying genetic and molecular causes.

Results

Using a population of 29,350 taurine dairy cows, we conducted association analyses for milk yield and composition traits, and identified highly significant QTL for milk yield, milk fat concentration, and milk protein concentration. Strikingly, protein concentration and milk yield appear to show co-located yet genetically distinct QTL. To attempt to understa

SUBMITTER: Lopdell TJ 

PROVIDER: S-EPMC6346582 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature