Resting-state functional brain networks in adults with a new diagnosis of focal epilepsy.

ABSTRACT:

Objectives

Newly diagnosed focal epilepsy (NDfE) is rarely studied, particularly using advanced neuroimaging techniques. Many patients with NDfE experience cognitive impairments, particularly with respect to memory, sustained attention, mental flexibility, and executive functioning. Cognitive impairments have been related to alterations in resting-state functional brain networks in patients with neurological disorders. In the present study, we investigated whether patients with NDfE had altered connectivity in large-scale functional networks using resting-state functional MRI.

Methods

We recruited 27 adults with NDfE and 36 age- and sex-matched healthy controls. Resting-state functional MRI was analyzed using the Functional Connectivity Toolbox (CONN). We investigate reprodu

SUBMITTER: Alonazi BK 

PROVIDER: S-EPMC6346674 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature