Cost-effectiveness of influenza vaccine strategies for the elderly in South Korea.

ABSTRACT:

Objectives

Despite a high vaccine uptake rate of over 80% in South Korea, the disease burden of influenza is still high among the elderly, which may be due to low effectiveness of vaccines. Therefore, the cost-effectiveness of use among the elderly was analyzed in order to compare the current trivalent influenza vaccine (TIV) with a quadrivalent influenza vaccine (QIV) or MF59-adjuvanted trivalent influenza vaccine (ATIV).

Methods

A static lifetime Markov model was used. It was assumed that the model would be repeated until individuals reached the age of 100. Cost-effectiveness was analyzed across three age groups (65-74 years, 75-84 years, and ≥85 years), and the at-risk group was studied.

Results

Compared to the TIV, the QIV was expected to reduce the number of infl

SUBMITTER: Yun JW 

PROVIDER: S-EPMC6347274 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature