Trauma induced acute kidney injury.

ABSTRACT:

Background

Injured patients are at risk of developing acute kidney injury (AKI), which is associated with increased morbidity and mortality. The aim of this study is to describe the incidence, timing, and severity of AKI in a large trauma population, identify risk factors for AKI, and report mortality outcomes.

Methods

A prospective observational study of injured adults, who met local criteria for trauma team activation, and were admitted to a UK Major Trauma Centre. AKI was defined by the Kidney Disease Improving Global Outcomes (KDIGO) criteria. Multivariable logistic regression and Cox proportional hazard modelling was used to analyse parameters associated with AKI and mortality.

Results

Of the 1410 patients enrolled in the study, 178 (12.6%) developed AKI. Age; in

SUBMITTER: Perkins ZB 

PROVIDER: S-EPMC6347290 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature