Risk factors for hospitalization of patients with chikungunya virus infection at sentinel hospitals in Puerto Rico.

ABSTRACT:

Background

Hospitalization of patients during outbreaks of chikungunya virus has been reported to be uncommon (0.5-8.7%), but more frequent among infants and the elderly. CHIKV was first detected in Puerto Rico in May 2014. We enrolled patients with acute febrile illness (AFI) presenting to two hospital emergency departments in Puerto Rico and tested them for CHIKV infection to describe the frequency of detection of CHIKV-infected patients, identify risk factors for hospitalization, and describe patients with severe manifestations.

Methodology/principal findings

Serum specimens were collected from patients with AFI and tested by rRT-PCR. During May-December 2014, a total of 3,035 patients were enrolled, and 1,469 (48.4%) had CHIKV infection. A total of 157 (10.7%) CHIKV-infe

SUBMITTER: Hsu CH 

PROVIDER: S-EPMC6347300 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature