Predictors of urinary phthalate biomarker concentrations in postmenopausal women.

ABSTRACT:

Background

Phthalates are ubiquitous endocrine disrupting chemicals present in a wide variety of consumer products. However, the personal characteristics associated with phthalate exposure are unclear.

Objectives

We sought to describe personal, behavioral, and reproductive characteristics associated with phthalate metabolite concentrations in an ongoing study nested within the Women's Health Initiative (WHI).

Materials and methods

We measured thirteen phthalate metabolites in two or three archived urine samples collected in 1993-2001 from each of 1257 WHI participants (2991 observations). We fit multivariable generalized estimating equation models to predict urinary biomarker concentrations from personal, behavioral, and reproductive characteristics.

Results

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SUBMITTER: Reeves KW 

PROVIDER: S-EPMC6347530 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature