Chronic and acute stress monitoring by electrophysiological signals from adrenal gland.

ABSTRACT: We present electrophysiological (EP) signals correlated with cellular cell activities in the adrenal cortex and medulla using an adrenal gland implantable flexible EP probe. With such a probe, we could observe the EP signals from the adrenal cortex and medulla in response to various stress stimuli, such as enhanced hormone activity with adrenocorticotropic hormone, a biomarker for chronic stress response, and an actual stress environment, like a forced swimming test. This technique could be useful to continuously monitor the elevation of cortisol level, a useful indicator of chronic stress that potentially causes various diseases.

SUBMITTER: Sunwoo SH 

PROVIDER: S-EPMC6347678 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature