Multivariate analysis of genomic variables, effective population size, and mutation rate.

ABSTRACT:

Objective

The relationship between genomic variables (genome size, gene number, intron size, and intron number) and evolutionary forces has two implications. First, they help to unravel the mechanism underlying genome evolution. Second, they provide a solution to the debate over discrepancy between genome size variation and organismal complexity. Previously, a clear correlation between genomic variables and effective population size and mutation rate (Neu) led to an important hypothesis to consider random genetic drift as a major evolutionary force during evolution of genome size and complexity. But recent reports also support natural selection as the leading evolutionary force. As such, the debate remains unresolved.

Results

Here, we used a multivariate method to explore th

SUBMITTER: Bhattachan P 

PROVIDER: S-EPMC6347809 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature