Development and performance evaluation of a GIS-based metric to assess exposure to airborne pollutant emissions from industrial sources.

ABSTRACT:

Background

Dioxins are environmental and persistent organic carcinogens with endocrine disrupting properties. A positive association with several cancers, including risk of breast cancer has been suggested.

Objectives

This study aimed to develop and assess performances of an exposure metric based on a Geographic Information System (GIS) through comparison with a validated dispersion model to estimate historical industrial dioxin exposure for its use in a case-control study nested within a prospective cohort.

Methods

Industrial dioxin sources were inventoried over the whole French territory (n > 2500) and annual average releases were estimated between 1990 and 2008. In three selected areas (rural, urban and urban-costal), dioxin dispersion was modelled using SIRANE, an

SUBMITTER: Coudon T 

PROVIDER: S-EPMC6347831 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature