Association between benzodiazepine use and risks of chronic-onset poststroke pneumonia: a population-based cohort study.

ABSTRACT:

Objectives

To investigate the association between benzodiazepine (BZD) use and the risk of chronic-onset poststroke pneumonia.

Design

Population-based propensity-matched retrospective cohort study.

Setting

Taiwan's National Health Insurance Research Database.

Participants

Patients newly diagnosed with stroke between 2000 and 2012 were identified and, after propensity score matching, 7516 patients were enrolled. Among these, 3758 patients received BZDs after stroke while 3758 did not.

Outcome measures

HRs for developing pneumonia over 1 month after stroke according to BZD use were assessed using Cox proportional hazards regression models. Analyses according to cumulative defined daily doses (cDDDs) of BZDs and stratification for age and sex were also perf

SUBMITTER: Lin SM 

PROVIDER: S-EPMC6347861 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature