Population-based cohort of 500 patients with Gaucher disease in Israel.

ABSTRACT:

Objective

To characterise a population-based cohort of patients with Gaucher disease (GD) in Israel relative to the general population and describe sociodemographic and clinical differences by disease severity (ie, enzyme replacement therapy [ERT] use).

Design

A cross-sectional study was conducted.

Setting

Data from the Clalit Health Services electronic health record (EHR) database were used.

Participants

The study population included all patients in the Clalit EHR database identified as having GD as of 30 June 2014.

Results

A total of 500 patients with GD were identified and assessed. The majority were ≥18 years of age (90.6%), female (54.0%), Jewish (93.6%) and 34.8% had high socioeconomic status, compared with 19.0% in the general Clalit population. O

SUBMITTER: Jaffe DH 

PROVIDER: S-EPMC6347887 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature