Decrease in loop diuretic treatment from 2005 to 2014 in Swedish real-life patients with chronic heart failure.

ABSTRACT:

Purpose

Loop diuretics are recommended to treat congestive symptoms in patients with heart failure. However, observational studies have indicated that loop diuretic treatment in heart failure is associated with increased mortality. Therefore, loop diuretic discontinuation or dose reduction, when clinically possible, is recommended. Our aim was to study nationwide temporal trends in loop diuretic treatment from 2005 to 2014 in real-life patients with chronic heart failure.

Methods

Data from the nationwide Swedish National Patient, Prescribed Drug and Cause of Death Registers were linked. The annual proportions of patients with chronic heart failure treated with loop diuretics from 2005 to 2014 were calculated. In addition, the annual median loop diuretic doses (DDD) in patien

SUBMITTER: Paren P 

PROVIDER: S-EPMC6348069 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature