Emerging literature in the Microbiota-Brain Axis and Perinatal Mood and Anxiety Disorders.

ABSTRACT: Perinatal Mood and Anxiety Disorders (PMAD) are common and can cause significant morbidity and mortality for mother and child. A healthy perinatal period requires significant adaptations; however, systems can become imbalanced resulting in depressive and anxiety symptoms. The interface between the microbiome, the immune system, and the stress system may be a model for understanding mechanisms underlying PMAD. Emerging literature from general populations regarding immune, hormone, and HPA axis changes in relation to the microbiome combined with literature on immune, gonadotropin, and stress systems in the perinatal period provides a background. We systematically investigated literature in the developing field of the microbiome in relation to PMAD. Our inclusion criteria were 1) reporting me

SUBMITTER: Rackers HS 

PROVIDER: S-EPMC6348074 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature