A controlled comparison of thickness, volume and surface areas from multiple cortical parcellation packages.

ABSTRACT:

Background

Cortical parcellation is an essential neuroimaging tool for identifying and characterizing morphometric and connectivity brain changes occurring with age and disease. A variety of software packages have been developed for parcellating the brain's cortical surface into a variable number of regions but interpackage differences can undermine reproducibility. Using a ground truth dataset (Edinburgh_NIH10), we investigated such differences for grey matter thickness (GM_th), grey matter volume (GM_vol) and white matter surface area (WM_sa) for the superior frontal gyrus (SFG), supramarginal gyrus (SMG), and cingulate gyrus (CG) from 4 parcellation protocols as implemented in the FreeSurfer, BrainSuite, and BrainGyrusMapping (BGM) software packages

SUBMITTER: Mikhael SS 

PROVIDER: S-EPMC6348615 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature