The Influence of Carrier Oils on the Antimicrobial Activity and Cytotoxicity of Essential Oils.

ABSTRACT: The topical use of essential oils requires dilution into a carrier oil; however, scientific evidence regarding the antimicrobial efficacy and cytotoxicity when a carrier oil is combined with an essential oil is lacking. This study sets out to determine the antimicrobial activity and cytotoxicity of 23 essential oils combined with six known carrier oils. Gas chromatography-mass spectrometry/flame ionization detector (GC-MS/FID) was used to characterize the methyl esters of the carrier oils. The antimicrobial activity of the carrier oils alone and in combination with the essential oils was investigated using the broth microdilution assay against 11 skin pathogens and the cytotoxicity was determined using the brine shrimp lethality assay. The interactive profiles of the combinations for both

SUBMITTER: Orchard A 

PROVIDER: S-EPMC6348851 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature