Barnaba: software for analysis of nucleic acid structures and trajectories.

ABSTRACT: RNA molecules are highly dynamic systems characterized by a complex interplay between sequence, structure, dynamics, and function. Molecular simulations can potentially provide powerful insights into the nature of these relationships. The analysis of structures and molecular trajectories of nucleic acids can be nontrivial because it requires processing very high-dimensional data that are not easy to visualize and interpret. Here we introduce Barnaba, a Python library aimed at facilitating the analysis of nucleic acid structures and molecular simulations. The software consists of a variety of analysis tools that allow the user to (i) calculate distances between three-dimensional structures using different metrics, (ii) back-calculate experimental data from three-dimensional structures, (iii

SUBMITTER: Bottaro S 

PROVIDER: S-EPMC6348988 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature