Stereotactic Ablative Radiation Therapy for Unresectable Colorectal Oligometastases.

ABSTRACT:

Purpose

Patients with oligometastatic colorectal cancer have demonstrated excellent clinical outcomes with surgical resection of hepatic and pulmonary metastases. Stereotactic ablative radiation therapy (SABR) has emerged as an alternative local therapy for nonsurgical candidates. Herein, we report the oncologic and patient-reported quality-of-life (PR-QoL) outcomes for a subset of patients with oligometastatic colorectal cancer who were treated in a prospective phase 2 multicenter clinical trial.

Methods and materials

Patients with a pathologically proven diagnosis of oligometastatic colorectal cancer were enrolled as part of a prospective study. SABR dose and fractionation schedules were dependent on the lesion location and size. Patient follow-up occurred 6 weeks after co

SUBMITTER: Sutera P 

PROVIDER: S-EPMC6349603 | biostudies-literature | 2019 Jan-Mar

REPOSITORIES: biostudies-literature