Nutritional, metabolic and genetic considerations to optimise regenerative medicine outcome for knee osteoarthritis.

ABSTRACT: Knee osteoarthritis (KOA) is a multifactorial degenerative disorder of joints, affecting the world's population over the age of 65 and with a higher prevalence in females. KOA is responsible for many age associated joint problems such as stiffness and pain. Conventional methods for managing KOA such as nonsteroidal anti-inflammatory drugs (NSAID) may not improve pain or alter the disease progression and may have adverse side effects. Non-pharmacological management of OA is fundamental to management of functional limitations and provides effective symptom relief but has not shown that disease progression can be altered. Regenerative medicine is a relatively new approach which aims to induce cellular regeneration and promote self-healing through minimally invasive methods. The use of regener

SUBMITTER: Hafsi K 

PROVIDER: S-EPMC6349648 | biostudies-literature | 2019 Jan-Feb

REPOSITORIES: biostudies-literature