The Association of Oxidative Stress Status with Open-Angle Glaucoma and Exfoliation Glaucoma: A Systematic Review and Meta-Analysis.

ABSTRACT:

Purpose

To systematically evaluate the associations between oxidative stress status and different types of glaucoma.

Design

Systematic review and meta-analysis.

Methods

We searched PubMed, EMBASE, and the Web of Science for randomized controlled trials written in the English language between January 1, 1990, and November 30, 2016. A random effects model was used to estimate oxidative stress status along with weighted mean differences and 95% confidence intervals (CIs). A funnel plot analysis and Egger's test were performed to assess potential publication bias.

Main outcome measures

Oxidative stress status was abnormal and different in patients with OAG (open-angle glaucoma) and EXG (exfoliation glaucoma).

Results

Blood TAS (total antioxidant status) was

SUBMITTER: Tang B 

PROVIDER: S-EPMC6350588 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature