Altered amygdala circuits underlying valence processing among manic and depressed phases in bipolar adults.

ABSTRACT:

Background

Disruptions in affective processing characterize mood disorders, yet the neural mechanisms underlying internal state dependency in affective processes are not well understood. The present work presents a pilot investigation into state dependency among neural circuits known to be involved in processing affective information, by examining acute manic and depressive mood phases in adults with bipolar disorder and major depressive disorder.

Methods

The present study probed affective processes with a well-validated passive picture-viewing task amongst acutely manic (n = 8) or acutely depressed (bipolar depression: n = 11; major depression: n = 15) mood-disordered adults during functional magnetic resonance imaging .

Results

Beta-series correlation analyses seede

SUBMITTER: Man V 

PROVIDER: S-EPMC6351166 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature