Calour: an Interactive, Microbe-Centric Analysis Tool.

ABSTRACT: Microbiome analyses can be challenging because microbial strains are numerous, and often, confounding factors in the data set are also numerous. Many tools reduce, summarize, and visualize these high-dimensional data to provide insight at the community level. However, they lose the detailed information about each taxon and can be misleading (for example, the well-known horseshoe effect in ordination plots). Thus, multiple methods at different levels of resolution are required to capture the full range of microbial patterns. Here we present Calour, a user-friendly data exploration tool for microbiome analyses. Calour provides a study-centric data model to store and manipulate sample-by-feature tables (with features typically being operational taxonomic units) and their associated metadata.

SUBMITTER: Xu ZZ 

PROVIDER: S-EPMC6351725 | biostudies-literature | 2019 Jan-Feb

REPOSITORIES: biostudies-literature