Prevalence of underlying gastrointestinal malignancies in iron-deficient heart failure.

ABSTRACT:

Aims

Anaemia and iron deficiency (ferritin level < 100 or 100-300 μg/L with transferrin saturation < 20%) are prevalent in heart failure. Mechanistically, iron deficiency is linked to poor intestinal uptake, increased intestinal loss, and chronic inflammation. However, the prevalence of underlying gastrointestinal malignancies is not established in iron-deficient heart failure with or without anaemia.

Methods and results

Patients followed up in a single-centre, heart failure database with baseline registration of haemoglobin and iron status were retrospectively evaluated. The proportion of patients undergoing upper and lower gastrointestinal endoscopy between inclusion and censoring was determined. Afterwards, the prevalence of biopsy that confirmed intestinal malignancies i

SUBMITTER: Martens P 

PROVIDER: S-EPMC6351899 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature