Socioeconomic Status and the Gut Microbiome: A TwinsUK Cohort Study.

ABSTRACT: Socioeconomic inequalities in health and mortality are well established, but the biological mechanisms underlying these associations are less understood. In parallel, the gut microbiome is emerging as a potentially important determinant of human health, but little is known about its broader environmental and social determinants. We test the association between gut microbiota composition and individual- and area-level socioeconomic factors in a well-characterized twin cohort. In this study, 1672 healthy volunteers from twin registry TwinsUK had data available for at least one socioeconomic measure, existing fecal 16S rRNA microbiota data, and all considered co-variables. Associations with socioeconomic status (SES) were robust to adjustment for known health correlates of the microbiome; con

SUBMITTER: Bowyer RCE 

PROVIDER: S-EPMC6351927 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature