Metabolic Signature Differentiated Diabetes Mellitus from Lipid Disorder in Elderly Taiwanese.

ABSTRACT: Aging is a complex progression of biological processes and is the causal contributor to the development of diabetes mellitus (DM). DM is the most common degenerative disease and is the fifth leading cause of death in Taiwan, where the trend of DM mortality has been steadily increasing. Metabolomics, important branch of systems biology, has been mainly utilized to understand endogenous metabolites in biological systems and their dynamic changes as they relate to endogenous and exogenous factors. The purpose of this study was to elucidate the metabolomic profiles in elderly people and its relation to lipid disorder (LD). We collected 486 elderly individuals aged ≥65 years and performed untargeted and targeted metabolite analysis using nuclear magnetic resonance (NMR) spectroscopy and liquid

SUBMITTER: Lo CJ 

PROVIDER: S-EPMC6352219 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature