Antihyperuricemia, Antioxidant, and Antibacterial Activities of Tridax procumbens L.

ABSTRACT: Tridax procumbens L. is a medicinal plant and used as a drink to treat bronchial catarrh, diarrhea, dysentery and liver diseases. In this study, we evaluated the potential use of T. procumbens to treat hyperuricemia, oxidative stress, and bacterial infection. Ethyl acetate extract of this plant was separated to different fractions by column chromatography (CC) using chloroform and methanol as eluents and subjected to xanthine oxidase (XO) inhibitory, antioxidant, and antibacterial assays. The results showed that the F45⁻47 fraction exhibited the strongest XO inhibitory activity (IC50 = 133.17 µg/mL), while the F48⁻50 fraction possessed maximum antioxidant activity assessed by DPPH (2,2-diphenyl-2-picrylhydrazyl) and ABTS (2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) assays (IC50

SUBMITTER: Andriana Y 

PROVIDER: S-EPMC6352254 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature