Age at Menarche and Blood Pressure in Pregnancy.

ABSTRACT:

Objectives

To investigate whether age at menarche is related to maternal blood pressure in pregnancy and, if so, whether obesity and insulin resistance can modify the associations.

Study design

Analysis of data collected from 438 pregnant women from the longitudinal and prospective Cambridge Baby Growth Study.

Main outcome

Testing associations between questionnaire-derived age at menarche and blood pressure measurements in pregnancy collected from hospital notes, and investigating whether any associations were altered by maternal pre-pregnancy body mass index (BMI) and insulin resistance.

Measures

Mean arterial blood pressure at four time points across pregnancy, age at menarche, (Homeostasis Model Assessment) insulin resistance around week 28 of pregnancy.

SUBMITTER: Petry CJ 

PROVIDER: S-EPMC6352955 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature