Dataset Information

Air pollution, urgent asthma medical visits and the modifying effect of neighborhood asthma prevalence.

ABSTRACT:

Background

Social and environmental stressors may modify associations between environmental pollutants and asthma symptoms. We examined if neighborhood asthma prevalence (higher: HAPN vs. lower: LAPN), a surrogate for underlying risk factors for asthma, modified the relationship between pollutants and urgent asthma visits.

Methods

Through zip code, home addresses were linked to New York City Community Air Survey's land use regression model for street-level, annual average nitrogen dioxide (NO₂), particulate matter (PM_2.5), elemental carbon (EC), summer average ozone (O₃), winter average sulfur dioxide (SO₂) concentrations. Poisson regression models were fit to estimate the association (prevalence ratio, PR) between pollutant exposures and seeking urgent asthma care.

Results

All pollutants, except O₃ were higher in HAPN than LAPN (P < 0.01). Neighborhood asthma prevalence modified the relationship between pollutants and urgent asthma (P-interaction < 0.01, for NO₂ and SO₃). Associations between pollutants and urgent asthma were observed only in LAPN (NO₂: PR = 1.38, P = 0.01; SO₃: PR = 1.85, P = 0.04). No association was observed between pollutants and urgent asthma among children in HAPN (P > 0.05).

Conclusions

Relationships between modeled street-level pollutants and urgent asthma were stronger in LAPN compared to HAPN. Social stressors that may be more prevalent in HAPN than LAPN, could play a greater role in asthma exacerbations in HAPN vs. pollutant exposure alone.

SUBMITTER: Lovinsky-Desir S

PROVIDER: S-EPMC6353679 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Publications

Air pollution, urgent asthma medical visits and the modifying effect of neighborhood asthma prevalence.

Lovinsky-Desir Stephanie S Acosta Luis M LM Rundle Andrew G AG Miller Rachel L RL Goldstein Inge F IF Jacobson Judith S JS Chillrud Steven N SN Perzanowski Matthew S MS

Pediatric research 20181018 1

<h4>Background</h4>Social and environmental stressors may modify associations between environmental pollutants and asthma symptoms. We examined if neighborhood asthma prevalence (higher: HAPN vs. lower: LAPN), a surrogate for underlying risk factors for asthma, modified the relationship between pollutants and urgent asthma visits.<h4>Methods</h4>Through zip code, home addresses were linked to New York City Community Air Survey's land use regression model for street-level, annual average nitrogen ...[more]

PMID: 30337671

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Project description:BackgroundPrevious studies of short-term ambient air pollution exposure and asthma morbidity in the United States have been limited to a small number of cities and/or pollutants and with limited consideration of effects across ages.ObjectivesTo estimate acute age group-specific effects of fine and coarse particulate matter (PM), major PM components, and gaseous pollutants on emergency department (ED) visits for asthma during 2005-2014 across the United States.MethodsWe acquired ED visit and air quality data in regions surrounding 53 speciation sites in 10 states. We used quasi-Poisson log-linear time-series models with unconstrained distributed exposure lags to estimate site-specific acute effects of air pollution on asthma ED visits overall and by age group (1-4, 5-17, 18-49, 50-64, and 65+ y), controlling for meteorology, time trends, and influenza activity. We then used a Bayesian hierarchical model to estimate pooled associations from site-specific associations.ResultsOur analysis included 3.19 million asthma ED visits. We observed positive associations for multiday cumulative exposure to all air pollutants examined [e.g., 8-d exposure to PM2.5: rate ratio of 1.016 with 95% credible interval (CI) of (1.008, 1.025) per 6.3-μg/m3 increase, PM10-2.5: 1.014 (95% CI: 1.007, 1.020) per 9.6-μg/m3 increase, organic carbon: 1.016 (95% CI: 1.009, 1.024) per 2.8-μg/m3 increase, and ozone: 1.008 (95% CI: 0.995, 1.022) per 0.02-ppm increase]. PM2.5 and ozone showed stronger effects at shorter lags, whereas associations of traffic-related pollutants (e.g., elemental carbon and oxides of nitrogen) were generally stronger at longer lags. Most pollutants had more pronounced effects on children (<18 y old) than adults; PM2.5 had strong effects on both children and the elderly (>64 y old); and ozone had stronger effects on adults than children.ConclusionsWe reported positive associations between short-term air pollution exposure and increased rates of asthma ED visits. We found that air pollution exposure posed a higher risk for children and older populations. https://doi.org/10.1289/EHP11661.

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Dataset Information

Air pollution, urgent asthma medical visits and the modifying effect of neighborhood asthma prevalence.

Background

Methods

Results

Conclusions

Publications

Air pollution, urgent asthma medical visits and the modifying effect of neighborhood asthma prevalence.

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