1.7 micron optical coherence tomography for vaginal tissue characterization in vivo.

ABSTRACT:

Objectives

Optical coherence tomography (OCT) can noninvasively visualize in vivo tissue microstructure with high spatial resolution that approaches the histologic level. Currently, OCT studies in gynecology are few and limited to a conventional 1.3 μm center wavelength swept light source which provides high spatial resolution but limited penetration depth. Here, we present a novel endoscopic OCT system with improved penetration depth and high resolution.

Methods

A novel endoscopic OCT system was developed based on a 1.7 µm swept source laser, which is capable of deeper tissue penetration due to its longer wavelength. To evaluate the performance of system, we imaged the human vaginas in vivo with both conventional 1.3 and 1.7 μm endoscopic OCT systems.

Results

With th

SUBMITTER: Li Y 

PROVIDER: S-EPMC6353703 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature