Testing the feasibility and safety of feeding preterm infants fresh mother's own milk in the NICU: A pilot study.

ABSTRACT: Necrotizing enterocolitis (NEC) is the leading cause of death among infants born at <30 weeks' gestation, but donor human milk can reduce the incidence of NEC. Unfortunately, freezing or pasteurizing human milk deactivates beneficial bioactive components. We evaluated the feasibility, safety, and impact of feeding very preterm infants fresh (unprocessed) mother's own milk within 4 hours of expression. In our multicentre prospective cohort analytic study, we fed 109 control and 98 intervention infants previously frozen donor or mother's own milk; only the intervention group was fed fresh mother's own milk once daily from enrollment until 32 weeks' corrected age. Control group mothers could not commit to provide fresh milk daily and were less likely receive antenatal corticosteroids than mot

SUBMITTER: Sun H 

PROVIDER: S-EPMC6353969 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature