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Neurodevelopmental milestones and associated behaviours are similar among healthy children across diverse geographical locations.

ABSTRACT: It is unclear whether early child development is, like skeletal growth, similar across diverse regions with adequate health and nutrition. We prospectively assessed 1307 healthy, well-nourished 2-year-old children of educated mothers, enrolled in early pregnancy from urban areas without major socioeconomic or environmental constraints, in Brazil, India, Italy, Kenya and UK. We used a specially developed psychometric tool, WHO motor milestones and visual tests. Similarities across sites were measured using variance components analysis and standardised site differences (SSD). In 14 of the 16 domains, the percentage of total variance explained by between-site differences ranged from 1.3% (cognitive score) to 9.2% (behaviour score). Of the 80 SSD comparisons, only six were >±0.50 units of the pooled SD for the corresponding item. The sequence and timing of attainment of neurodevelopmental milestones and associated behaviours in early childhood are, therefore, likely innate and universal, as long as nutritional and health needs are met.

SUBMITTER: Villar J

PROVIDER: S-EPMC6353986 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Neurodevelopmental milestones and associated behaviours are similar among healthy children across diverse geographical locations.

Villar José J Fernandes Michelle M Purwar Manorama M Staines-Urias Eleonora E Di Nicola Paola P Cheikh Ismail Leila L Ochieng Roseline R Barros Fernando F Albernaz Elaine E Victora Cesar C Kunnawar Naina N Temple Sophie S Giuliani Francesca F Sandells Tamsin T Carvalho Maria M Ohuma Eric E Jaffer Yasmin Y Noble Alison A Gravett Michael M Pang Ruyan R Lambert Ann A Bertino Enrico E Papageorghiou Aris A Garza Cutberto C Stein Alan A Bhutta Zulfiqar Z Kennedy Stephen S

Nature communications 20190130 1

It is unclear whether early child development is, like skeletal growth, similar across diverse regions with adequate health and nutrition. We prospectively assessed 1307 healthy, well-nourished 2-year-old children of educated mothers, enrolled in early pregnancy from urban areas without major socioeconomic or environmental constraints, in Brazil, India, Italy, Kenya and UK. We used a specially developed psychometric tool, WHO motor milestones and visual tests. Similarities across sites were meas ...[more]

PMID: 30700709

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Neurodevelopmental milestones and associated behaviours are similar among healthy children across diverse geographical locations.

Publications

Neurodevelopmental milestones and associated behaviours are similar among healthy children across diverse geographical locations.

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