APID database: redefining protein-protein interaction experimental evidences and binary interactomes.

ABSTRACT: The collection and integration of all the known protein-protein physical interactions within a proteome framework are critical to allow proper exploration of the protein interaction networks that drive biological processes in cells at molecular level. APID Interactomes is a public resource of biological data (http://apid.dep.usal.es) that provides a comprehensive and curated collection of `protein interactomes' for more than 1100 organisms, including 30 species with more than 500 interactions, derived from the integration of experimentally detected protein-to-protein physical interactions (PPIs). We have performed an update of APID database including a redefinition of several key properties of the PPIs to provide a more precise data integration and to avoid false duplicated records. This i

SUBMITTER: Alonso-Lopez D 

PROVIDER: S-EPMC6354026 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature