Optimizing influenza vaccine policies for controlling 2009-like pandemics and regular outbreaks.

ABSTRACT:

Background

This study examined the effectiveness of various vaccine policies against influenza. The transmission rate was calculated by use of the time-series influenza-like illness case during the year of 2009 and recent epidemics in Taiwan.

Methods

We developed a stochastic compartmental model to analyze the transmission of influenza, where the population was stratified by location and age group, and the vaccine distribution was considered using the current policy. The simulation study compared the previous vaccine policy and a new policy with expanded coverage and various lengths of the vaccination campaign. The sensitivity analysis investigated different levels of vaccine efficacy to confirm the robustness of the recommended policies.

Results

Doubling vaccine cove

SUBMITTER: Chen SI 

PROVIDER: S-EPMC6354664 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature