Gestational Weight Gain and Offspring Bone Mass: Different Associations in Healthy Weight Versus Overweight Women.

ABSTRACT: Weight management strategies during pregnancy reduce child cardiometabolic risk. However, because maternal weight has an overall positive correlation with offspring bone mass, pregnancy weight management could adversely affect child bone health. We aimed to estimate associations between gestational weight gain (GWG) and bone mineralization in the offspring at 7 years of age, and test early pregnancy body mass index (BMI) as an effect modifier. We analyzed prospective data from 2167 mother-child pairs from the Generation XXI birth cohort who underwent whole-body dual-energy X-ray absorptiometry at 7 years of age. GWG was analyzed as a continuous measure and using the Institute of Medicine categories. In the whole sample and for each early pregnancy BMI category (under/normal weight and over

SUBMITTER: Monjardino T 

PROVIDER: S-EPMC6354939 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature