Differences in mood instability in patients with bipolar disorder type I and II: a smartphone-based study.

ABSTRACT: BACKGROUND:Mood instability in bipolar disorder is associated with a risk of relapse. This study investigated differences in mood instability between patients with bipolar disorder type I and type II, which previously has been sparingly investigated. METHODS:Patients with bipolar disorder type I (n = 53) and type II (n = 31) used a daily smartphone-based self-monitoring system for 9 months. Data in the present reflect 15.975 observations of daily collected smartphone-based data on patient-evaluated mood. RESULTS:In models adjusted for age, gender, illness duration and psychopharmacological treatment, patients with bipolar disorder type II experienced more mood instability during depression compared with patients with bipolar disorder type I (B: 0.27, 95% CI 0.007; 0.53, p = 0.044), but low

SUBMITTER: Faurholt-Jepsen M 

PROVIDER: S-EPMC6355891 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature