Craniobot: A computer numerical controlled robot for cranial microsurgeries.

ABSTRACT: Over the last few decades, a plethora of tools has been developed for neuroscientists to interface with the brain. Implementing these tools requires precisely removing sections of the skull to access the brain. These delicate cranial microsurgical procedures need to be performed on the sub-millimeter thick bone without damaging the underlying tissue and therefore, require significant training. Automating some of these procedures would not only enable more precise microsurgical operations, but also facilitate widespread use of advanced neurotechnologies. Here, we introduce the "Craniobot", a cranial microsurgery platform that combines automated skull surface profiling with a computer numerical controlled (CNC) milling machine to perform a variety of cranial microsurgical procedures on mice.

SUBMITTER: Ghanbari L 

PROVIDER: S-EPMC6355931 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature