Evidence for Strong Kinship Influence on the Extent of Linkage Disequilibrium in Cultivated Common Beans.

ABSTRACT: Phaseolus vulgaris is an important grain legume for human consumption. Recently, association mapping studies have been performed for the species aiming to identify loci underlying quantitative variation of traits. It is now imperative to know whether the linkage disequilibrium (LD) reflects the true association between a marker and causative loci. The aim of this study was to estimate and analyze LD on a diversity panel of common beans using ordinary r² and r² extensions which correct bias due to population structure (r_S²), kinship (r_V²), and both (r_VS²). A total of 10,362 single nucleotide polymorphisms (SNPs) were identified by genotyping by sequencing (GBS), and polymorphisms were found to be widely distributed along the 11 chromosomes.

SUBMITTER: Diniz AL 

PROVIDER: S-EPMC6356217 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature